Artificial Intelligence in Label Free Microscopy : Biological Cell Classification by Time Stretch - Mahjoubfar, Ata

Artificial Intelligence in Label Free Microscopy : Biological Cell Classification by Time Stretch

Ata Mahjoubfar

Yayınevi: Springer Verlag

Yayın tarihi: 05/2017

ISBN: 9783319514475

Yazar : Claire Lifan Chen Bahram Jalali

Ciltli | İngilizce | 170 Sayfa | 16,21x23,6x1,6 cm.

Tür: Genel Mühendislik

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This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis.

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